Interviews for the public considering the hygiene hypothesis, the COVID pandemic, and consequences for the human microbiome (in German)

27. Juli 2021

Gespräch mit Wissenschaftsautorin Sabine Jossé für mein-allergie-portal.com zum Einfluss der Corona-Maßnahmen auf das menschliche Mikrobiom.

Link zum Gespräch: „Mikrobiom: Welchen Einfluss haben die Corona-Maßnahmen?“

7. Juni 2021

Gespräch mit Wissenschaftsautorin Susanne Wedlich für Spektrum.de zur Bedeutung der Mikroorganismen für unsere Gesundheit.
Covid-19_ Infektionsschutz könnte auch das Mikrobiom stören – Spektrum der Wissenschaft

April 2021

Artikel in der GIT Labor-Fachzeitschrift zu „Neue Bedrohungen für das Mikrobiom- Hygienemaßnahmen im Rahmen der Covid-19 Pandemie.

Zum Artikel online im Wiley Analytical Science Magazine.

Interview mit Verena Fischer (Hopp und Frenz Content House) über die hohe Bedeutung von Mikroorganismen für unsere Gesundheit und weshalb wir ohne sie gar nicht existieren können.

2021

Paper Bosch TCG (2021) Taking a microscale look at symbiotic interactions—and why it matters (Commentary), Proc Natl Acad Sci USA Vol. 118 No. 31 e2110874118

PaperGiez C, Klimovich A, Bosch TCG (2021) Neurons interact with the microbiome: an evolutionary-informed perspective. Neuroforum, 27(2): 89–98 https://www.degruyter.com/document/

PaperGiez C, Bosch TCG (2021). Beating in on a stable partnership. Nat Rev Microbiol. 2021 Jun 4. doi: 10.1038/s41579-021-00575-y. Epub ahead of print. PMID: 34089009.

Bosch TCG and McFall-Ngai M (2021) Animal development in the microbial world: Re-thinking the conceptual framework.  Academic Press, 2021. https://doi.org/10.1016/bs.ctdb.2020.11.007;  https://www.sciencedirect.com/science/article/pii/S0070215320301290)   

McFall-Ngai M and Bosch TCG (2021) Animal development in the microbial world: The power of experimental model systems. Current Topics in Developmental Biology. Academic Press 2021. ISSN 0070-2153. https://doi.org/10.1016/bs.ctdb.2020.10.002.

PaperFinlay B, Amato KR, Azad M, Blaser MJ, Bosch TCG et al (2021) The hygiene hypothesis during a pandemic: consequences for the human microbiome. Proc Natl Acad Sci USA 118(6) e2010217118 https://www.pnas.org/content/pnas/118/6/e2010217118.full.pdf

Great News for Interdisciplinary Research at Kiel University

We received funding for a new Collaborative Research Centre (CRC) “Neurotronics: Bio-inspired Information Pathways“. In close collaboration between electro engineers and evolutionary biologists at Kiel University, the CRC will explore novel hardware technologies for novel bio-inspired computing architectures paving the way towards a paradigm change in information processing. Projects by Thomas Bosch and by Alexander Klimovich aim to model functional circuit growth including sensory information processing of the nervous system of Hydra to derive fundamental biological principles of neuronal circuit growth. Based on a spatiotemporal map of the nervous system of developing Hydra polyps, an electrical circuit mimicking the activity patterns of light-modulated body contractions will be synthesized. A wave digital emulation will reveal how the nervous system of a Hydra hatchling processes visual sensory information related to light stimulation.

New Book: Cellular Dialogues in the Holobiont

Thomas Bosch recently edited the book “Cellular Dialogues in the Holobiont” together with Mike Hadfield from the University of Hawaii.

From the preface:

A dialogue that matters: microbe–host interactions in protists, plants, and animals.
Animal evolution appears intimately linked to the presence of microbes. A continuously increasing number of studies demonstrate that individuals from sponges to humans are not solitary, isolated entities, but consist of complex communities of many species that likely coevolved during a billion years of coexistence (McFall-Ngai et al., 2013). This progress is due in large part to the application of “metagenomic” methods: a series of experimental and computational approaches that allows a microbial community’s composition to be defined by DNA sequencing without having to culture its members. This work has yielded catalogues of microbial species, many previously unknown and belonging to all three domains of life, as well as lists of millions of microbial genes collectively known as a host’s microbiome. Research on host–microbe interactions has become an emerging cross-disciplinary field. Contrary to the classical view that microbes are primarily pathogenic and disease-causing, there is now a multitude of studies indicating that a host-specific microbiome provides functions related to metabolism, immunity, development, and environmental adaptation to its animal, plant, or fungal host. Similarly, microbes have been documented as important for environmental sensing, inducing colony formation and sexual reproduction in choanoflagellates, and contributing to developmental transitions and life history traits such as development pace and longevity. Similarly, the microbiome of plants impacts the phenotype and fitness of the plant host. It has become increasingly clear that animals, plants, and fungi evolved in a microbial world and that multicellular organisms rely on their associated microbes to function. Symbiosis appears as a general principle in eukaryotic evolution.

Interview mit Thomas Bosch zur Bedeutung des Mikrobioms in Zeiten von Covid-19