How do multicellular organisms assess and control their size ?

In a Nature Comm. paper published in July 2019 the Bosch lab shows that size in Hydra is controlled by Wnt- and TGF-β signaling. Insulin-like peptide receptor (INSR) and forkhead box protein O (FoxO) are important genetic drivers of size determination controlling the same developmental regulators.

Learn more about this research in a (German) radio interview: